Immunology 2023
A bout Conference
SESSIONS AND TRACKS
Track 1. Drug Food & Food Allergy
Drug allergies are a set of symptoms caused by an allergic reaction to a drug. A drug allergy encompasses an immune response in the body that develops an allergic reaction to a medicine. If you develop a rash, hives or difficulty breathing after taking certain medications, you may have a drug allergy. As with other allergic reactions, these symptoms of drug allergy can occur when your body’s immune system becomes sensitive to a substance in the medication, identifies it as a foreign invader and releases chemicals to defend against it.
Food allergy is caused when the body falsely makes an antibody (IgE) to fight against a specific food. When the food is next (or sometimes is just in contact with the skin) it provokes an immune system response which results in the commute of histamine and other substances in the body. These cause various symptoms, depending on where in the body they are exposed. For example, in the gut they may result in abdominal pain, vomiting and diarrhoea; in the skin, itching and swelling (rash or nettle rash), in the upper airways, a runny nose or sneezing; in the lower airways, a wheeze or cough.
Track 2. Ocular & Skin Allergy
The eye, like the respiratory tract, can be a site of acute allergic reactions. Ocular allergy also called Allergic conjunctivitis occurs when something allergic to irritate the conjunctiva. This is the sensitive membrane covering the eye and the inside of the eyelid. As all allergies, allergic conjunctivitis starts when the immune system recognises an otherwise innocuous substance as an allergen. This causes your immune system to overreact and produce antibodies called Immunoglobulin (IgE). These antibodies drive to cells that release chemicals which cause an allergic reaction. In this case, allergic reactions include eyes that water, itch, hurt or become red or swollen.
Irritated skin can be caused by a many factors. These include immune system disorders, medications and infections. When an allergen is responsible for initiating an immune system response, then it is an allergic skin condition. When skin is contacted by a substance, body’s immune system is triggered thinking the substance as a foreign agent, because of this skin becomes sensitive & develops allergy. Contact with substance such as detergents, soaps or cleaning supplies causes skin allergy.
Track 3. ENT Allergy
Allergy affecting Ear, Nose, and Throat comprises ENT allergy. Seasonal as well as long lasting allergies can contribute to enduring sinusitis, bronchitis, as well as ear problems. Allergies are diagnosed through the patient's history, physical examination as well as allergy testing. Once the distinct allergens are identified prevention techniques as well as immunotherapy can be used in addition to antihistamines in order to obtain optimal results.
- Allergic rhinitis
- Otorhinolaryngology
- Rhinitis
- Allergic salute
Track 4. Infection & Immunity
The invasion of foreign organism on a host body for its growth and multiplication is termed as infection. The infection can lead to infectious diseases/ transmissible disease/ communicable disease. The infection can be caused by any infectious agents and their toxins causing several immune reactions like allergy, inflammation etc. Immune or allergic reactions arise upon infection due to the role of Host immune system to maintain immunity in the body. The infectious agents may be bacteria, virus, fungus, parasites, protozoans etc. As the agents vary, so does the route of transmission to enter into the host body and also the diseases, diagnosis and treatments. The immunity of an individual must be well enough to combat such infections. Immunity will be innately present in an individual from the mother through placenta and also later on through breast milk. Immunity will also be acquired by an individual during his/her lifetime through exposure to several allergens, microorganisms and foreign substances.
Effects of infectious disease
- Infectious agents and route of transmission
- Infectious diseases: diagnosis & treatment
- Cellular and hormonal immunity
- Virology and Infectious Diseases
Track: 5. Allergy Diagnosis & Medicine
Allergic diseases are the outcome of allergic inflammation that occurs as a result of an interaction between the environment and the patient's immune system resulting in the release of histamine and other pro-inflammatory mediators. Knowing exactly what body is allergic to can help lessen or prevent exposure and treat the reactions. Laboratory investigations are a useful tool in the diagnosis and management of allergic diseases and can provide aids to diagnose and assess disease activity.
- Patch test
Track 6. Asthma & COPD
The condition of swollen, inflamed and extra mucosal lung airways upon infections or exposure to allergen is asthma/ bronchial asthma and the epigenetics of asthma varies accordingly. Asthma is long term chronic inflammatory disease of the lung airways caused by any specific allergen (Allergic asthma) or any other genetic / environmental factor (Non-Allergic Asthma) involving symptoms like wheezing, coughing, breath shortnessand chest tightness. Research is going in a rapid pace due to increase in the asthma attack cases, mostly in children (Pediatric Asthma). Asthma allergy immunotherapy and several advances in treatment can be discussed in allergy conference like this.
Chronic obstructive pulmonary disease or COPD is a set of chronic inflammatory lung disease. The disease is contributed by Emphysema and chronic bronchitis. Emphysema is the condition in which the alveoli get destroyed and chronic bronchitis is the condition where inflammation of the lining of the bronchial tubes takes place. People who smoke even after having asthma or people who have long term exposure to chemical fumes, vapours and dusts in the workplace, fumes from burning fuel for cooking and heating in poorly ventilated homes are at risk of developing COPD. Rare cause for COPD is genetic disorder: alpha-1-antitrypsin deficiency. COPD symptoms don’t appear initially hence research in COPD diagnosis in enhancing as misdiagnosis can increase the risk of COPD in the person cause heart disease, lung cancer and so on.
Types of asthma
- Chronic obstructive pulmonary diseases (COPD)
- Pediatric Asthma
- Treatments
Track 7. Pediatric Allergy
Allergies are among the most common conditions affecting children. Child’s immune system fights against infections. If a child has allergies, their immune system wrongly reacts to things that are usually harmless. Pet dander, pollen, dust, mold spores, insect stings, food, and medications are examples of such things. This reaction may cause their body to reciprocate with health problems such as asthma, hay fever, hives, eczema (a rash), or a very severe and unusual reaction called anaphylaxis.
Track 8. Allergens & Allergies
Allergies are one of the most common chronic diseases. A chronic disease lasts a long time or occurs often. An allergy occurs when the body’s immune system sees a substance as harmful and overreacts to it. The substances that cause allergic reactions are allergens. When someone has allergies, their immune system makes an antibody called immunoglobulin E (IgE). These antibodies respond to allergens.
Track 9. Allergy Prevention & Risk Factors
Allergies can be prevented by identifying & avoiding the ones which cause allergy to the body. One of the biggest causes of allergy is house dust mites, pets, mould spores, food allergies, insect bites stings, when trying to identify what causes or deteriorate your allergic symptoms, track your activities and what you eat, when symptoms occur and what seems to help. Host factors responsible for risk of allergy are heredity, sex, race and age. Exposure to allergens has been identified as an influential environmental factor, whereas passive smoking and pollution may act as an adjuvant.
Track 10. Allergy and Inflammation
Allergy is one of the most adverse immune reaction faced worldwide by people which is next accompanied by inflammation. The set of conditions caused by Hypersensitivity of the immune system in response to any foreign substance is allergy/ allergic diseases. It may arise due to genetic or environmental factors. The causative agents are termed as allergen and they may be food, drug, dust, pollen, animal dander &fur etc. varying for each individual. Mostly allergen immunotherapy is the advanced therapeutics method to treat the allergies. Allergic and Inflammatory Reactions are caused by the immune system but if the reaction becomes adverse then the condition becomes chronic for an individual. The causative agents for such adverse reactions could be genetic, environmental, pathogenic and synthetic compounds. The localized body part which gets red, swollen, hot and painful after an injury or infection is an condition termed as inflammation and it might be due to allergy: Allergic inflammation or due to tumour. Inflammation can be acute or chronic and it consists of different types based on the part of inflammation
Track 11.Cellular Immunology:
Cellular Immunology distributes unique examinations worried with the immunological exercises of cells in test or clinical circumstances. The response to pathogens is created by the collaborations and exercises of the substantial number of assorted cell sorts required in the insusceptible reaction.
- Pattern acknowledgment receptors and cell encapsulation
- Cellular antioxidant activities
- B-cell and T-cell receptors
- Cellular automata and specialist based models
Track 12. Clinical immunology:
Clinical immunology is the investigation of sicknesses caused by scatters of the safe framework (disappointment, unusual activity, and threatening development of the cell components of the framework). It likewise includes maladies of different frameworks, where resistant responses have an influence in the pathology and clinical components.
- Immunological parts of disease
- Immunological technique
Track 13. Pediatric Immunology:
A kid experiencing sensitivities or different issues with his insusceptible framework is eluded as pediatric immunology. Kid's safe framework battles against contaminations. On the off chance that the kid has sensitivities, their insusceptible framework wrongly responds to things that are typically safe. Pet dander, dust, tidy, shape spores, creepy crawly stings, nourishment, and solutions are cases of such things. This response may make their body react with medical issues, for example, asthma, feed fever, hives, skin inflammation (a rash), or an exceptionally serious and irregular response called hypersensitivity. In some cases, if your tyke's insusceptible framework is not working right, he may experience the ill effects of incessant, extreme, as well as phenomenal diseases. Cases of such contaminations are sinusitis (irritation of at least one of the sinuses), pneumonia (disease of the lung), thrush (a parasite contamination in the mouth), and abscesses (accumulations of discharge encompassed by excited tissue) that continue returning.
- Pediatric Allergies
- Severe reactions to foods, insect stings, and medications (anaphylaxis)
- Eczema (atopic dermatitis)
- Hay fever (allergic rhinitis)
- Hives (welts)
- Asthma
- Pulmonology
- Hay fever (allergic rhinitis)
Track 14. Diagnostic Immunology:
The specificity of the bond amongst immune response and antigen has made the immunizer an astounding apparatus for the recognition of substances by an assortment of analytic strategies. Antibodies particular for a coveted antigen can be conjugated with an isotopic (radio) or fluorescent mark or with a shading framing catalyst keeping in mind the end goal to identify it. Notwithstanding, the likeness between a few antigens can prompt false positives and different mistakes in such tests by antibodies cross-responding with antigens that aren't correct matches.
Indicative immunology has impressively progressed because of the improvement of computerized methods. New innovation considers sparing examples, reagents, and diminishing cost. The fate of analytic immunology confronts challenges in the inoculation field for insurance against HIV and as hostile to growth treatment
- Diagnostic and restorative part of small scale RNA in immunediseases
- Advanced diagnostic tools
- Diagnostic biomarkers
Track 15. Reproductive Immunology:
Some fruitfulness centers offer tests and medicines which depend on the possibility that invulnerable cells in your body can "dismiss" a baby, keeping an effective pregnancy. This is a zone of solution called conceptive immunology and the medicines are called immunosuppressive treatments.The hypothesis behind regenerative immunology has been broadly defamed, and there is no proof that immunosuppressive treatments enhance your shot of getting pregnant. Conceptive immunology alludes to a field of solution that reviews communications (or the nonappearance of them) between the resistant framework and segments identified with the regenerative framework, for example, maternal safe resilience towards the embryo, or immunological associations over the blood-testis boundary. The idea has been utilized by fruitfulness facilities to clarify the richness issues, repetitive premature deliveries and pregnancy intricacies watched when this condition of immunological resilience is not effectively accomplish
- Immunogenetics
- Immunocontraceptive vaccine
- Immunological paradox of pregnancy
- Mucosal immunity and sexually transmitted infections and Diseases
Track 16. Viral Immunology:
Viral immunology is the investigation of viral contaminations and resistant reactions towards viral diseases which can cause malicious impact on the elements of the cells. It incorporates both DNA and RNA viral diseases. Infections are unequivocally immunogenic and create 2 sorts of invulnerable reactions; humoral and cell. T and B cells don't by and large perceive similar epitopes exhibit on a similar infection. B cells see the free unaltered proteins in their local 3-D compliance though T cells typically observe the Ag in a denatured frame in conjunction with MHC atoms. The qualities of the safe response to a similar infection may vary in various people contingent upon their hereditary constitutions.
- Viral invasion, evasion, and resistance
- Pathogenesis of viral infection in body
- Innate immunity against viral pathogens
- Viral proteins
Track 17. Fungal Immunology:
Fungal organisms that cause infection, many are opportunistic pathogens, which mean they just purpose ailment in specific situations for example, when the safe framework winds up noticeably debilitated. For example, chemotherapy, immunosuppressive medications and HIV disease all outcome implying that growth can then more effortlessly contaminate these defenseless patients.
- Host-Fungal Pathogen Interactions
- Immune responses against fungal pathogens
- Structures and Signals that Impact Fungal Immunity
Track 18. Ocular Immunology:
Ocular immunology is an exceedingly concentrated branch of medication dedicated to diagnosing and treating patients with incendiary eye maladies. These infections can marginally diminish vision or prompt extreme vision misfortune. Ophthalmologists utilize the general term, uveitis, when alluding to the scope of incendiary sicknesses that influence the uvea. Moreover, uveitis is utilized to depict any provocative sickness that produces swelling and decimates eye tissues, including inside the retina. It's normally connected with foundational sicknesses, for example, rheumatoid joint inflammation. Anatomically, uveitis is characterized into foremost, moderate, back, and panuveitic shapes, contingent upon which part of the eye is influenced. Regardless of the arrangement, Sabates Eye Centers can deal with it all.
- Ocular Manifestations of Pathogenic Infection
-
Epidemiology and Clinical Trials in Ocular Inflammation
- Allergy and Ocular Surface
- Orbital Inflammation and Infection
- Immunology of Ocular Tumors
Track 19. Food & Agricultural Immunology:
Food sensitivities are expanding in predominance at a higher rate than can be clarified by hereditary components, recommending a part for up 'til now unidentified ecological variables. The intestinal epithelium shapes the interface between the outer condition and the mucosal invulnerable framework, and developing information recommend that the collaboration between intestinal epithelial cells and mucosal dendritic cells is of specific significance in deciding the result of safe reactions to dietary antigens. Presentation to sustenance allergens through non-oral courses, specifically through the skin, is progressively perceived as a conceivably imperative factor in the expanding rate of nourishment sensitivity. There are many open inquiries on the part of natural elements, for example, dietary variables and microbiota, in the improvement of nourishment hypersensitivity, however information recommend that both have an essential modulatory impact on the mucosal insusceptible framework.
- Development of diagnostic systems
- ligand based assays
- Application of ligand based assays
- Food Allergy or Sensitivity to Agricultural Chemicals
Track 20. Immunotherapy and Vaccine:
Immunotherapy is an exceptionally dynamic territory of tumor research. Numerous researchers and specialists around the globe are concentrating better approaches to utilize immunotherapy to treat disease. Some of these are talked about here.
Immunization is a natural readiness that enhances insusceptibility to specific illness. It contains specific specialists that looks like a sickness causing microorganism as well as empowers body's resistant framework to perceive the remote operators. Immunizations are dead or inactivated creatures or filtered items gotten from them. Entire life form immunizations refined macromolecules as antibodies, recombinant antibodies, DNA antibodies. The invulnerable framework perceives antibody operators as remote, crushes them, and "recollects that" them.
- Advancements in vaccine development, novel tools- machinary used
- Next-generation conjugate vaccines
- Vaccines for pregnant women
- T cell based immunotherapies and vaccines
- Immunotherapy for autoimmune diseases
- Vaccine adjuvants
- Development of prophylactic vaccines against cancer and infectious diseases
MARKET ANALYSIS
Resistant interceded provocative maladies measure an appallingly fundamental plan of unending issue that influence 5– 7% of western peoples. Regardless of the way that they're regularly novel to the extent their signs and key patient economics, they're pathophysiological related; being depicted by deregulation of safe pathways relate ruined a graceless response. Overall, ailment adjusting against rheumatic pharmaceutical, to an incredible degree summed up grouping of general little molecule based masters, square measure used in the primary line treatment of those illnesses. This square measure supplemented in a couple of cases by shorter-term adrenal cortical steroid therapeutic care, another characterization of to an extraordinary degree summed up pros.
Notwithstanding, as these medications generally speaking disregard to summon relate degree attractive semi-ceaseless response, an outsized second-line therapeutic care fragment has ascended in these business divisions, starting with the support of Remicade (infliximab) and (etanercept) in 1998. This zone includes generally of premium general life shape Antibodies (mAbs), those square measure extraordinarily fiscally useful due to their expansive utilize and high regard. Notwithstanding the way that the licenses for a couple of those mAbs either have authoritatively invalid or square measure because of pass all through the check total, the market is foreseen to aptitude continuing with advancement.
Regardless of the way that the licenses for a couple of those mAbs either have viably invalid or are an immediate aftereffect of slip by all through the gauge whole, the market is foreseen to expertise continuing with advancement, from $61.5 billion out of 2015 to $74.2 billion out of 2022, at a compound yearly rate of two.71%.